Uncommon Side Effects of Xarelto
The anticoagulant drug class accounts for a consistently high number of reported side effects and deaths. The Institute for Safe Medication Practices (ISMP), a consumer safety group, ranked Xarelto as the most dangerous domestic drug for life-threatening side effects. The drug had the most direct reports to the FDA regarding serious injury. ISMP’s study showed that out of the 10,674 reported cases of injury, 8,643 involved hemorrhaging.
While the easy to use aspect of the drug appeals to many consumers, ISMP found that the once daily dosage of Xarelto contributes to higher bleeding risk. In contrast, the once a day dosage also results in times during the day where levels are lower and may not hold up to a safe standard of preventing strokes.
The study concluded that drug companies made a major mistake when developing and marketing this new generation of anticoagulants. Instead of working on improving the safety of these drugs, they focused on their ease of use.
The most common side effect of Xarelto is uncontrollable bleeding and blood loss, including major bleeding events.
Other side effects of Xarelto include:
- Numb or tingling muscles
- Pain in one’s arms or legs
- Muscle pain
- Loss of ability to control movement
- Abnormal liver function
- Reduced platelet levels
- Hemorrhaging bleeding from the rectum
- Intestinal or abdominal bleeds
- Bleeding in the brain
- Muscle spasms
- Difficulty breathing or swallowing
- Back pain
- Dizziness Headache
- Leg weakness
- Bladder dysfunction
- Bowel dysfunction
Xarelto is often prescribed to patients from Orthopedic surgeons after hip-replacement or knee-replacement surgery, which brings on another set of possible side effects amounting to wound infections and leakage. Studies have shown higher risks of wound complications, greater return-to-surgery rates and higher infection rates.
Xarelto’s lack of an antidote can make bleedings situations all the more dire and difficult to counteract. If someone using Xarelto experiences any of the following, they should seek medical attention right away.
- Frequent nose bleeds
- Unusual bleeding in the gums
- Red, pink or brown urine
- Severe uncontrolled bleeding
- Bright red or black stool that looks like tar
- Vaginal bleeding or menstrual bleeding that is heavier than normal
- Wounds with pain, swelling or new drainage at the site
- Coughing up blood or blood clots
- Headaches, feeling weak and dizzy
- Blood in vomit or vomit that looks like “coffee grounds”